Breast cancer

Breast cancer is the most diagnosed cancer among women worldwide with an estimated 2.3 million new cases in 2022, and the most frequently diagnosed cancer in women in 157 countries, accounting for 1 in 4 cancer cases. It is the second most frequent cancer amongst both sexes representing one in every 9 cancers. Breast cancer is the leading cause of death from cancer in women with an estimated 669,418 deaths in 2022, with a disproportionate number of these deaths occurring in low-resource settings.

UICC's Podcast on breast cancer

What is breast cancer?

Breast cancer occurs when abnormal cells in the breast grow out of control. The cells usually form a tumour that can often be seen on an x-ray or felt as a lump. If spread outside the breast to other parts of the body, it becomes advanced breast cancer. When breast cancer spreads to other parts of the body (such as the liver, lungs, bones or brain), it is said to have metastasised, and is referred to as metastatic breast cancer.

Survival rates for breast cancer are very high when the cancer is detected early and where treatment is available. The five-year breast-cancer survival rates exceed 90% in high-income countries, compared to 66% in India and 40% in South Africa. Unfortunately, many breast cancer cases are diagnosed at an advanced stage in many low- and middle-income countries, when the cancer is more difficult to treat, is more expensive to do so, and is usually incurable.

Despite advances and progress seen in breast cancer in recent years, current data highlights that by 2040, breast cancer incidence will increase 40%, and mortality is expected increase by 50%, with a disproportionate number of cases and deaths expected to occur in low-resource settings.

Addressing breast cancer

The World Health Organization’s Global Breast Cancer Initiative (GBCI), established in 2021, brings together stakeholders from around the world with the shared goal of reducing breast cancer by 2.5% per year, which over a 20-year period would save 2.5 million lives.

In March 2022, GBCI launched an implementation framework that describes three key pillars with specific targets to achieve these objectives.

Pillar 1

60%
early stage diagnosis

Health promotion and early detection
Achieve diagnosis of at least 60% of invasive breast cancers at stage I or II.

Pillar 2

60-day
diagnosis

Timely diagnosis

Evaluation, imaging, tissue sampling and pathology completed within 60 days.

Pillar 3

80%
treatment completion

Comprehensive breast cancer management
80% undergo full courses of multimodality treatment and successfully return home.

UICC's work on breast cancer

UICC Breast Cancer programme

Leveraging established UICC Capacity Building programmes and convening platforms, the Breast Cancer programme aims to strengthen the capacity of key breast cancer actors to increase their impact and engage them in support of the WHO Global Breast Cancer Initiative (GBCI)’s targets.

Through a series of activities and opportunities, the programme aims to deliver the following key outcomes:

Accelerate the development of breast cancer leaders
Strengthen organisational capacities of breast cancer organisations, including patient groups 
Support the development of the health workforce in breast cancer 
Support national action on breast cancer in responding to key areas and needs in breast cancer control
Strengthen networks and collaborations in breast cancer at a national, regional and global level
Unite the voice of the breast cancer community, including patient groups, to advocate for more effective breast cancer control

The programme builds bridges between a vast array of stakeholders (cancer organisations, patient groups, healthcare providers, private sector, governments and multilateral agencies) at regional and global levels to catalyse engagement towards the WHO GBCI targets, with a focus on action in low and middle income countries.

Learn more about UICC’s Breast Cancer programme

Learn more about UICC's actions on breast cancer