Ligue Nationale contre le Cancer is a provide help to association founded in 1918 after WWI when cancer was recognized to be a spreading epidemic. The League's goal is to cancer patients, their family and friends. Since its founding, the League has developed into a strong network and leads the fight against cancer on three levels; research, promotion of screening and prevention, and care for patients and their loved ones.

The league is a federation of 103 departmental committees that are active in relaying the mission of the administrative council and the national scientific council. The league has more than 720,000 members, 30,000 volunteers and 300 salaried staff who keep the network active by leading the fight and generating the essential resources of the league.

Ligue National contre le Cancer became full UICC member in 1968.